diff --git a/Source/Core/Common/GL/GLInterface/AGL.h b/Source/Core/Common/GL/GLInterface/AGL.h
index f3c3bd47cf..5f9a138282 100644
--- a/Source/Core/Common/GL/GLInterface/AGL.h
+++ b/Source/Core/Common/GL/GLInterface/AGL.h
@@ -17,7 +17,7 @@ class cInterfaceAGL : public cInterfaceBase
 {
 public:
   void Swap() override;
-  bool Create(void* window_handle, bool core) override;
+  bool Create(void* window_handle, bool stereo, bool core) override;
   bool MakeCurrent() override;
   bool ClearCurrent() override;
   void Shutdown() override;
diff --git a/Source/Core/Common/GL/GLInterface/AGL.mm b/Source/Core/Common/GL/GLInterface/AGL.mm
index 37fec99440..bdae829cbc 100644
--- a/Source/Core/Common/GL/GLInterface/AGL.mm
+++ b/Source/Core/Common/GL/GLInterface/AGL.mm
@@ -51,12 +51,15 @@ void cInterfaceAGL::Swap()
 
 // Create rendering window.
 // Call browser: Core.cpp:EmuThread() > main.cpp:Video_Initialize()
-bool cInterfaceAGL::Create(void* window_handle, bool core)
+bool cInterfaceAGL::Create(void* window_handle, bool stereo, bool core)
 {
-  NSOpenGLPixelFormatAttribute attr[] = {NSOpenGLPFADoubleBuffer, NSOpenGLPFAOpenGLProfile,
-                                         core ? NSOpenGLProfileVersion3_2Core :
-                                                NSOpenGLProfileVersionLegacy,
-                                         NSOpenGLPFAAccelerated, 0};
+  NSOpenGLPixelFormatAttribute attr[] = {
+      NSOpenGLPFADoubleBuffer,
+      NSOpenGLPFAOpenGLProfile,
+      core ? NSOpenGLProfileVersion3_2Core : NSOpenGLProfileVersionLegacy,
+      NSOpenGLPFAAccelerated,
+      stereo ? NSOpenGLPFAStereo : static_cast<NSOpenGLPixelFormatAttribute>(0),
+      0};
   NSOpenGLPixelFormat* fmt = [[NSOpenGLPixelFormat alloc] initWithAttributes:attr];
   if (fmt == nil)
   {
diff --git a/Source/Core/Common/GL/GLInterface/BGL.cpp b/Source/Core/Common/GL/GLInterface/BGL.cpp
index 7cc9070a49..ed2670efc5 100644
--- a/Source/Core/Common/GL/GLInterface/BGL.cpp
+++ b/Source/Core/Common/GL/GLInterface/BGL.cpp
@@ -13,7 +13,7 @@ void cInterfaceBGL::Swap()
   m_gl->SwapBuffers();
 }
 
-bool cInterfaceBGL::Create(void* window_handle, bool core)
+bool cInterfaceBGL::Create(void* window_handle, bool stereo, bool core)
 {
   m_window = static_cast<BWindow*>(window_handle);
 
diff --git a/Source/Core/Common/GL/GLInterface/BGL.h b/Source/Core/Common/GL/GLInterface/BGL.h
index aeb678f804..b26e5e3fc8 100644
--- a/Source/Core/Common/GL/GLInterface/BGL.h
+++ b/Source/Core/Common/GL/GLInterface/BGL.h
@@ -14,7 +14,7 @@ class cInterfaceBGL final : public cInterfaceBase
 public:
   void Swap() override;
   void* GetFuncAddress(const std::string& name) override;
-  bool Create(void* window_handle, bool core) override;
+  bool Create(void* window_handle, bool stereo, bool core) override;
   bool MakeCurrent() override;
   bool ClearCurrent() override;
   void Shutdown() override;
diff --git a/Source/Core/Common/GL/GLInterface/EGL.cpp b/Source/Core/Common/GL/GLInterface/EGL.cpp
index 9deb4f20e7..32cd705d73 100644
--- a/Source/Core/Common/GL/GLInterface/EGL.cpp
+++ b/Source/Core/Common/GL/GLInterface/EGL.cpp
@@ -111,7 +111,7 @@ void cInterfaceEGL::DetectMode()
 
 // Create rendering window.
 // Call browser: Core.cpp:EmuThread() > main.cpp:Video_Initialize()
-bool cInterfaceEGL::Create(void* window_handle, bool core)
+bool cInterfaceEGL::Create(void* window_handle, bool stereo, bool core)
 {
   EGLint egl_major, egl_minor;
   bool supports_core_profile = false;
diff --git a/Source/Core/Common/GL/GLInterface/EGL.h b/Source/Core/Common/GL/GLInterface/EGL.h
index 2352f9b646..69a351851f 100644
--- a/Source/Core/Common/GL/GLInterface/EGL.h
+++ b/Source/Core/Common/GL/GLInterface/EGL.h
@@ -38,7 +38,7 @@ public:
   void SwapInterval(int interval) override;
   void SetMode(GLInterfaceMode mode) override { s_opengl_mode = mode; }
   void* GetFuncAddress(const std::string& name) override;
-  bool Create(void* window_handle, bool core) override;
+  bool Create(void* window_handle, bool stereo, bool core) override;
   bool Create(cInterfaceBase* main_context) override;
   bool MakeCurrent() override;
   bool ClearCurrent() override;
diff --git a/Source/Core/Common/GL/GLInterface/GLX.cpp b/Source/Core/Common/GL/GLInterface/GLX.cpp
index d3550c688f..f6fea067ef 100644
--- a/Source/Core/Common/GL/GLInterface/GLX.cpp
+++ b/Source/Core/Common/GL/GLInterface/GLX.cpp
@@ -43,7 +43,7 @@ void cInterfaceGLX::Swap()
 
 // Create rendering window.
 // Call browser: Core.cpp:EmuThread() > main.cpp:Video_Initialize()
-bool cInterfaceGLX::Create(void* window_handle, bool core)
+bool cInterfaceGLX::Create(void* window_handle, bool stereo, bool core)
 {
   dpy = XOpenDisplay(nullptr);
   int screen = DefaultScreen(dpy);
@@ -87,6 +87,8 @@ bool cInterfaceGLX::Create(void* window_handle, bool core)
                           0,
                           GLX_DOUBLEBUFFER,
                           True,
+                          GLX_STEREO,
+                          stereo ? True : False,
                           None};
   int fbcount = 0;
   GLXFBConfig* fbc = glXChooseFBConfig(dpy, screen, visual_attribs, &fbcount);
diff --git a/Source/Core/Common/GL/GLInterface/GLX.h b/Source/Core/Common/GL/GLInterface/GLX.h
index 20feba27e0..ae019ccbf9 100644
--- a/Source/Core/Common/GL/GLInterface/GLX.h
+++ b/Source/Core/Common/GL/GLInterface/GLX.h
@@ -24,7 +24,7 @@ public:
   void SwapInterval(int Interval) override;
   void Swap() override;
   void* GetFuncAddress(const std::string& name) override;
-  bool Create(void* window_handle, bool core) override;
+  bool Create(void* window_handle, bool stereo, bool core) override;
   bool MakeCurrent() override;
   bool ClearCurrent() override;
   void Shutdown() override;
diff --git a/Source/Core/Common/GL/GLInterface/WGL.cpp b/Source/Core/Common/GL/GLInterface/WGL.cpp
index 3e500f5866..4d4647e838 100644
--- a/Source/Core/Common/GL/GLInterface/WGL.cpp
+++ b/Source/Core/Common/GL/GLInterface/WGL.cpp
@@ -200,7 +200,7 @@ bool cInterfaceWGL::PeekMessages()
 
 // Create rendering window.
 // Call browser: Core.cpp:EmuThread() > main.cpp:Video_Initialize()
-bool cInterfaceWGL::Create(void* window_handle, bool core)
+bool cInterfaceWGL::Create(void* window_handle, bool stereo, bool core)
 {
   if (!window_handle)
     return false;
@@ -219,12 +219,14 @@ bool cInterfaceWGL::Create(void* window_handle, bool core)
   s_backbuffer_width = twidth;
   s_backbuffer_height = theight;
 
-  static constexpr PIXELFORMATDESCRIPTOR pfd = {
+  const DWORD stereo_flag = stereo ? PFD_STEREO : 0;
+  static const PIXELFORMATDESCRIPTOR pfd = {
       sizeof(PIXELFORMATDESCRIPTOR),  // Size Of This Pixel Format Descriptor
       1,                              // Version Number
       PFD_DRAW_TO_WINDOW |            // Format Must Support Window
           PFD_SUPPORT_OPENGL |        // Format Must Support OpenGL
-          PFD_DOUBLEBUFFER,           // Must Support Double Buffering
+          PFD_DOUBLEBUFFER |          // Must Support Double Buffering
+          stereo_flag,                // Could Support Quad Buffering
       PFD_TYPE_RGBA,                  // Request An RGBA Format
       32,                             // Select Our Color Depth
       0,
diff --git a/Source/Core/Common/GL/GLInterface/WGL.h b/Source/Core/Common/GL/GLInterface/WGL.h
index e6f0ff3c66..efa9655713 100644
--- a/Source/Core/Common/GL/GLInterface/WGL.h
+++ b/Source/Core/Common/GL/GLInterface/WGL.h
@@ -14,7 +14,7 @@ public:
   void SwapInterval(int interval) override;
   void Swap() override;
   void* GetFuncAddress(const std::string& name) override;
-  bool Create(void* window_handle, bool core) override;
+  bool Create(void* window_handle, bool stereo, bool core) override;
   bool Create(cInterfaceBase* main_context) override;
   bool MakeCurrent() override;
   bool ClearCurrent() override;
diff --git a/Source/Core/Common/GL/GLInterfaceBase.h b/Source/Core/Common/GL/GLInterfaceBase.h
index b19f5698bc..4ffb7f5f53 100644
--- a/Source/Core/Common/GL/GLInterfaceBase.h
+++ b/Source/Core/Common/GL/GLInterfaceBase.h
@@ -34,7 +34,7 @@ public:
   virtual void SetMode(GLInterfaceMode mode) { s_opengl_mode = GLInterfaceMode::MODE_OPENGL; }
   virtual GLInterfaceMode GetMode() { return s_opengl_mode; }
   virtual void* GetFuncAddress(const std::string& name) { return nullptr; }
-  virtual bool Create(void* window_handle, bool core = true) { return true; }
+  virtual bool Create(void* window_handle, bool stereo = false, bool core = true) { return true; }
   virtual bool Create(cInterfaceBase* main_context) { return true; }
   virtual bool MakeCurrent() { return true; }
   virtual bool ClearCurrent() { return true; }
diff --git a/Source/Core/DolphinWX/VideoConfigDiag.cpp b/Source/Core/DolphinWX/VideoConfigDiag.cpp
index 2dc76ae456..30e93a6ff4 100644
--- a/Source/Core/DolphinWX/VideoConfigDiag.cpp
+++ b/Source/Core/DolphinWX/VideoConfigDiag.cpp
@@ -277,8 +277,9 @@ static wxString cache_efb_copies_desc =
 static wxString stereo_3d_desc =
     wxTRANSLATE("Selects the stereoscopic 3D mode. Stereoscopy allows you to get a better feeling "
                 "of depth if you have the necessary hardware.\nSide-by-Side and Top-and-Bottom are "
-                "used by most 3D TVs.\nAnaglyph is used for Red-Cyan colored glasses.\nHeavily "
-                "decreases emulation speed and sometimes causes issues.\n\nIf unsure, select Off.");
+                "used by most 3D TVs.\nAnaglyph is used for Red-Cyan colored glasses.\nHDMI 3D is "
+                "used when your monitor supports 3D display resolutions.\nHeavily decreases "
+                "emulation speed and sometimes causes issues.\n\nIf unsure, select Off.");
 static wxString stereo_depth_desc =
     wxTRANSLATE("Controls the separation distance between the virtual cameras.\nA higher value "
                 "creates a stronger feeling of depth while a lower value is more comfortable.");
@@ -622,8 +623,8 @@ VideoConfigDiag::VideoConfigDiag(wxWindow* parent, const std::string& title)
       szr_stereo->Add(new wxStaticText(page_enh, wxID_ANY, _("Stereoscopic 3D Mode:")), 0,
                       wxALIGN_CENTER_VERTICAL);
 
-      const wxString stereo_choices[] = {_("Off"), _("Side-by-Side"), _("Top-and-Bottom"),
-                                         _("Anaglyph"), _("Nvidia 3D Vision")};
+      const wxString stereo_choices[] = {_("Off"),      _("Side-by-Side"), _("Top-and-Bottom"),
+                                         _("Anaglyph"), _("HDMI 3D"),      _("Nvidia 3D Vision")};
       wxChoice* stereo_choice =
           CreateChoice(page_enh, Config::GFX_STEREO_MODE, wxGetTranslation(stereo_3d_desc),
                        vconfig.backend_info.bSupports3DVision ? ArraySize(stereo_choices) :
diff --git a/Source/Core/VideoBackends/D3D/D3DBase.cpp b/Source/Core/VideoBackends/D3D/D3DBase.cpp
index 327fece109..ad989f4188 100644
--- a/Source/Core/VideoBackends/D3D/D3DBase.cpp
+++ b/Source/Core/VideoBackends/D3D/D3DBase.cpp
@@ -26,13 +26,7 @@ CREATEDXGIFACTORY PCreateDXGIFactory = nullptr;
 HINSTANCE hDXGIDll = nullptr;
 int dxgi_dll_ref = 0;
 
-typedef HRESULT(WINAPI* D3D11CREATEDEVICEANDSWAPCHAIN)(IDXGIAdapter*, D3D_DRIVER_TYPE, HMODULE,
-                                                       UINT, CONST D3D_FEATURE_LEVEL*, UINT, UINT,
-                                                       CONST DXGI_SWAP_CHAIN_DESC*,
-                                                       IDXGISwapChain**, ID3D11Device**,
-                                                       D3D_FEATURE_LEVEL*, ID3D11DeviceContext**);
 static D3D11CREATEDEVICE PD3D11CreateDevice = nullptr;
-D3D11CREATEDEVICEANDSWAPCHAIN PD3D11CreateDeviceAndSwapChain = nullptr;
 HINSTANCE hD3DDll = nullptr;
 int d3d_dll_ref = 0;
 
@@ -40,7 +34,7 @@ namespace D3D
 {
 ID3D11Device* device = nullptr;
 ID3D11DeviceContext* context = nullptr;
-static IDXGISwapChain* swapchain = nullptr;
+static IDXGISwapChain1* swapchain = nullptr;
 static ID3D11Debug* debug = nullptr;
 D3D_FEATURE_LEVEL featlevel;
 D3DTexture2D* backbuf = nullptr;
@@ -58,6 +52,8 @@ unsigned int xres, yres;
 
 bool bFrameInProgress = false;
 
+#define NUM_SWAPCHAIN_BUFFERS 2
+
 HRESULT LoadDXGI()
 {
   if (dxgi_dll_ref++ > 0)
@@ -99,12 +95,6 @@ HRESULT LoadD3D()
     MessageBoxA(nullptr, "GetProcAddress failed for D3D11CreateDevice!", "Critical error",
                 MB_OK | MB_ICONERROR);
 
-  PD3D11CreateDeviceAndSwapChain =
-      (D3D11CREATEDEVICEANDSWAPCHAIN)GetProcAddress(hD3DDll, "D3D11CreateDeviceAndSwapChain");
-  if (PD3D11CreateDeviceAndSwapChain == nullptr)
-    MessageBoxA(nullptr, "GetProcAddress failed for D3D11CreateDeviceAndSwapChain!",
-                "Critical error", MB_OK | MB_ICONERROR);
-
   return S_OK;
 }
 
@@ -172,7 +162,6 @@ void UnloadD3D()
     FreeLibrary(hD3DDll);
   hD3DDll = nullptr;
   PD3D11CreateDevice = nullptr;
-  PD3D11CreateDeviceAndSwapChain = nullptr;
 }
 
 void UnloadD3DCompiler()
@@ -276,14 +265,13 @@ HRESULT Create(HWND wnd)
     return hr;
   }
 
-  IDXGIFactory* factory;
-  IDXGIAdapter* adapter;
-  IDXGIOutput* output;
+  IDXGIFactory2* factory;
   hr = PCreateDXGIFactory(__uuidof(IDXGIFactory), (void**)&factory);
   if (FAILED(hr))
     MessageBox(wnd, _T("Failed to create IDXGIFactory object"), _T("Dolphin Direct3D 11 backend"),
                MB_OK | MB_ICONERROR);
 
+  IDXGIAdapter* adapter;
   hr = factory->EnumAdapters(g_ActiveConfig.iAdapter, &adapter);
   if (FAILED(hr))
   {
@@ -294,25 +282,6 @@ HRESULT Create(HWND wnd)
                  MB_OK | MB_ICONERROR);
   }
 
-  // TODO: Make this configurable
-  hr = adapter->EnumOutputs(0, &output);
-  if (FAILED(hr))
-  {
-    // try using the first one
-    IDXGIAdapter* firstadapter;
-    hr = factory->EnumAdapters(0, &firstadapter);
-    if (!FAILED(hr))
-      hr = firstadapter->EnumOutputs(0, &output);
-    if (FAILED(hr))
-      MessageBox(wnd, _T("Failed to enumerate outputs!\n")
-                      _T("This usually happens when you've set your video adapter to the Nvidia ")
-                      _T("GPU in an Optimus-equipped system.\n")
-                      _T("Set Dolphin to use the high-performance graphics in Nvidia's drivers ")
-                      _T("instead and leave Dolphin's video adapter set to the Intel GPU."),
-                 _T("Dolphin Direct3D 11 backend"), MB_OK | MB_ICONERROR);
-    SAFE_RELEASE(firstadapter);
-  }
-
   // get supported AA modes
   aa_modes = EnumAAModes(adapter);
 
@@ -324,45 +293,34 @@ HRESULT Create(HWND wnd)
     UpdateActiveConfig();
   }
 
-  DXGI_SWAP_CHAIN_DESC swap_chain_desc = {};
-  swap_chain_desc.BufferCount = 1;
+  DXGI_SWAP_CHAIN_DESC1 swap_chain_desc = {};
+  swap_chain_desc.BufferCount = NUM_SWAPCHAIN_BUFFERS;
   swap_chain_desc.BufferUsage = DXGI_USAGE_RENDER_TARGET_OUTPUT;
-  swap_chain_desc.OutputWindow = wnd;
   swap_chain_desc.SampleDesc.Count = 1;
   swap_chain_desc.SampleDesc.Quality = 0;
-  swap_chain_desc.Windowed =
-      !SConfig::GetInstance().bFullscreen || g_ActiveConfig.bBorderlessFullscreen;
+  swap_chain_desc.Format = DXGI_FORMAT_R8G8B8A8_UNORM;
+  swap_chain_desc.Scaling = DXGI_SCALING_STRETCH;
+  swap_chain_desc.SwapEffect = DXGI_SWAP_EFFECT_FLIP_SEQUENTIAL;
+  swap_chain_desc.Width = xres;
+  swap_chain_desc.Height = yres;
 
-  DXGI_OUTPUT_DESC out_desc = {};
-  output->GetDesc(&out_desc);
-
-  DXGI_MODE_DESC mode_desc = {};
-  mode_desc.Width = out_desc.DesktopCoordinates.right - out_desc.DesktopCoordinates.left;
-  mode_desc.Height = out_desc.DesktopCoordinates.bottom - out_desc.DesktopCoordinates.top;
-  mode_desc.Format = DXGI_FORMAT_R8G8B8A8_UNORM;
-  mode_desc.Scaling = DXGI_MODE_SCALING_UNSPECIFIED;
-  hr = output->FindClosestMatchingMode(&mode_desc, &swap_chain_desc.BufferDesc, nullptr);
-  if (FAILED(hr))
-    MessageBox(wnd, _T("Failed to find a supported video mode"), _T("Dolphin Direct3D 11 backend"),
-               MB_OK | MB_ICONERROR);
-
-  if (swap_chain_desc.Windowed)
-  {
-    // forcing buffer resolution to xres and yres..
-    // this is not a problem as long as we're in windowed mode
-    swap_chain_desc.BufferDesc.Width = xres;
-    swap_chain_desc.BufferDesc.Height = yres;
-  }
+  // By always creating a stereo swapchain we can toggle Quad-Buffered stereoscopy
+  // while the game is running.
+  swap_chain_desc.Stereo = TRUE;
 
 #if defined(_DEBUG) || defined(DEBUGFAST)
   // Creating debug devices can sometimes fail if the user doesn't have the correct
   // version of the DirectX SDK. If it does, simply fallback to a non-debug device.
   {
-    hr = PD3D11CreateDeviceAndSwapChain(
-        adapter, D3D_DRIVER_TYPE_UNKNOWN, nullptr,
-        D3D11_CREATE_DEVICE_SINGLETHREADED | D3D11_CREATE_DEVICE_DEBUG, supported_feature_levels,
-        NUM_SUPPORTED_FEATURE_LEVELS, D3D11_SDK_VERSION, &swap_chain_desc, &swapchain, &device,
-        &featlevel, &context);
+    hr = PD3D11CreateDevice(adapter, D3D_DRIVER_TYPE_UNKNOWN, nullptr,
+                            D3D11_CREATE_DEVICE_SINGLETHREADED | D3D11_CREATE_DEVICE_DEBUG,
+                            supported_feature_levels, NUM_SUPPORTED_FEATURE_LEVELS,
+                            D3D11_SDK_VERSION, &device, &featlevel, &context);
+
+    if (SUCCEEDED(hr))
+      hr = factory->CreateSwapChainForHwnd(device, hWnd, &swap_chain_desc, nullptr, nullptr,
+                                           &swapchain);
+
     // Debugbreak on D3D error
     if (SUCCEEDED(hr) && SUCCEEDED(device->QueryInterface(__uuidof(ID3D11Debug), (void**)&debug)))
     {
@@ -386,10 +344,14 @@ HRESULT Create(HWND wnd)
   if (FAILED(hr))
 #endif
   {
-    hr = PD3D11CreateDeviceAndSwapChain(
-        adapter, D3D_DRIVER_TYPE_UNKNOWN, nullptr, D3D11_CREATE_DEVICE_SINGLETHREADED,
-        supported_feature_levels, NUM_SUPPORTED_FEATURE_LEVELS, D3D11_SDK_VERSION, &swap_chain_desc,
-        &swapchain, &device, &featlevel, &context);
+    hr = PD3D11CreateDevice(adapter, D3D_DRIVER_TYPE_UNKNOWN, nullptr,
+                            D3D11_CREATE_DEVICE_SINGLETHREADED, supported_feature_levels,
+                            NUM_SUPPORTED_FEATURE_LEVELS, D3D11_SDK_VERSION, &device, &featlevel,
+                            &context);
+
+    if (SUCCEEDED(hr))
+      hr = factory->CreateSwapChainForHwnd(device, hWnd, &swap_chain_desc, nullptr, nullptr,
+                                           &swapchain);
   }
 
   if (FAILED(hr))
@@ -414,7 +376,6 @@ HRESULT Create(HWND wnd)
 
   SetDebugObjectName((ID3D11DeviceChild*)context, "device context");
   SAFE_RELEASE(factory);
-  SAFE_RELEASE(output);
   SAFE_RELEASE(adapter);
 
   ID3D11Texture2D* buf;
@@ -574,7 +535,7 @@ void Reset()
   GetClientRect(hWnd, &client);
   xres = client.right - client.left;
   yres = client.bottom - client.top;
-  D3D::swapchain->ResizeBuffers(1, xres, yres, DXGI_FORMAT_R8G8B8A8_UNORM, 0);
+  D3D::swapchain->ResizeBuffers(NUM_SWAPCHAIN_BUFFERS, xres, yres, DXGI_FORMAT_R8G8B8A8_UNORM, 0);
 
   // recreate back buffer texture
   ID3D11Texture2D* buf;
@@ -618,8 +579,11 @@ void EndFrame()
 
 void Present()
 {
+  UINT present_flags =
+      g_ActiveConfig.iStereoMode != STEREO_QUADBUFFER ? DXGI_PRESENT_STEREO_TEMPORARY_MONO : 0;
+
   // TODO: Is 1 the correct value for vsyncing?
-  swapchain->Present((UINT)g_ActiveConfig.IsVSync(), 0);
+  swapchain->Present((UINT)g_ActiveConfig.IsVSync(), present_flags);
 }
 
 HRESULT SetFullscreenState(bool enable_fullscreen)
diff --git a/Source/Core/VideoBackends/D3D/D3DBase.h b/Source/Core/VideoBackends/D3D/D3DBase.h
index dec8d5206f..288be59a9f 100644
--- a/Source/Core/VideoBackends/D3D/D3DBase.h
+++ b/Source/Core/VideoBackends/D3D/D3DBase.h
@@ -6,7 +6,7 @@
 
 #include <d3d11.h>
 #include <d3dcompiler.h>
-#include <dxgi.h>
+#include <dxgi1_2.h>
 #include <vector>
 
 #include "Common/Common.h"
diff --git a/Source/Core/VideoBackends/D3D/Render.cpp b/Source/Core/VideoBackends/D3D/Render.cpp
index 3fef05973b..027c3611c0 100644
--- a/Source/Core/VideoBackends/D3D/Render.cpp
+++ b/Source/Core/VideoBackends/D3D/Render.cpp
@@ -1220,12 +1220,16 @@ void Renderer::BlitScreen(TargetRectangle src, TargetRectangle dst, D3DTexture2D
     D3D11_VIEWPORT vp = CD3D11_VIEWPORT((float)dst.left, (float)dst.top, (float)dst.GetWidth(),
                                         (float)dst.GetHeight());
     D3D::context->RSSetViewports(1, &vp);
-    D3D::drawShadedTexQuad(src_texture->GetSRV(), src.AsRECT(), src_width, src_height,
-                           (g_Config.iStereoMode == STEREO_ANAGLYPH) ?
-                               PixelShaderCache::GetAnaglyphProgram() :
-                               PixelShaderCache::GetColorCopyProgram(false),
+
+    ID3D11PixelShader* pixelShader = (g_Config.iStereoMode == STEREO_ANAGLYPH) ?
+                                         PixelShaderCache::GetAnaglyphProgram() :
+                                         PixelShaderCache::GetColorCopyProgram(false);
+    ID3D11GeometryShader* geomShader = (g_ActiveConfig.iStereoMode == STEREO_QUADBUFFER) ?
+                                           GeometryShaderCache::GetCopyGeometryShader() :
+                                           nullptr;
+    D3D::drawShadedTexQuad(src_texture->GetSRV(), src.AsRECT(), src_width, src_height, pixelShader,
                            VertexShaderCache::GetSimpleVertexShader(),
-                           VertexShaderCache::GetSimpleInputLayout(), nullptr, Gamma);
+                           VertexShaderCache::GetSimpleInputLayout(), geomShader, Gamma);
   }
 }
 
diff --git a/Source/Core/VideoBackends/OGL/Render.cpp b/Source/Core/VideoBackends/OGL/Render.cpp
index 494a478501..3282489369 100644
--- a/Source/Core/VideoBackends/OGL/Render.cpp
+++ b/Source/Core/VideoBackends/OGL/Render.cpp
@@ -1196,6 +1196,16 @@ void Renderer::BlitScreen(TargetRectangle src, TargetRectangle dst, GLuint src_t
     post_processor->BlitFromTexture(src, leftRc, src_texture, src_width, src_height, 0);
     post_processor->BlitFromTexture(src, rightRc, src_texture, src_width, src_height, 1);
   }
+  else if (g_ActiveConfig.iStereoMode == STEREO_QUADBUFFER)
+  {
+    glDrawBuffer(GL_BACK_LEFT);
+    post_processor->BlitFromTexture(src, dst, src_texture, src_width, src_height, 0);
+
+    glDrawBuffer(GL_BACK_RIGHT);
+    post_processor->BlitFromTexture(src, dst, src_texture, src_width, src_height, 1);
+
+    glDrawBuffer(GL_BACK);
+  }
   else
   {
     post_processor->BlitFromTexture(src, dst, src_texture, src_width, src_height, 0);
diff --git a/Source/Core/VideoBackends/OGL/main.cpp b/Source/Core/VideoBackends/OGL/main.cpp
index f9bf7c069e..c00782ee70 100644
--- a/Source/Core/VideoBackends/OGL/main.cpp
+++ b/Source/Core/VideoBackends/OGL/main.cpp
@@ -167,7 +167,7 @@ bool VideoBackend::Initialize(void* window_handle)
 
   InitInterface();
   GLInterface->SetMode(GLInterfaceMode::MODE_DETECT);
-  if (!GLInterface->Create(window_handle))
+  if (!GLInterface->Create(window_handle, g_ActiveConfig.iStereoMode == STEREO_QUADBUFFER))
     return false;
 
   return true;
diff --git a/Source/Core/VideoBackends/Vulkan/PostProcessing.cpp b/Source/Core/VideoBackends/Vulkan/PostProcessing.cpp
index db8da49499..971de51180 100644
--- a/Source/Core/VideoBackends/Vulkan/PostProcessing.cpp
+++ b/Source/Core/VideoBackends/Vulkan/PostProcessing.cpp
@@ -41,11 +41,14 @@ void VulkanPostProcessing::BlitFromTexture(const TargetRectangle& dst, const Tar
                                            const Texture2D* src_tex, int src_layer,
                                            VkRenderPass render_pass)
 {
+  // If the source layer is negative we simply copy all available layers.
+  VkShaderModule geometry_shader =
+      src_layer < 0 ? g_object_cache->GetPassthroughGeometryShader() : VK_NULL_HANDLE;
   VkShaderModule fragment_shader =
       m_fragment_shader != VK_NULL_HANDLE ? m_fragment_shader : m_default_fragment_shader;
   UtilityShaderDraw draw(g_command_buffer_mgr->GetCurrentCommandBuffer(),
                          g_object_cache->GetPipelineLayout(PIPELINE_LAYOUT_STANDARD), render_pass,
-                         g_object_cache->GetPassthroughVertexShader(), VK_NULL_HANDLE,
+                         g_object_cache->GetPassthroughVertexShader(), geometry_shader,
                          fragment_shader);
 
   // Source is always bound.
diff --git a/Source/Core/VideoBackends/Vulkan/Renderer.cpp b/Source/Core/VideoBackends/Vulkan/Renderer.cpp
index 4800d99424..9a26df8548 100644
--- a/Source/Core/VideoBackends/Vulkan/Renderer.cpp
+++ b/Source/Core/VideoBackends/Vulkan/Renderer.cpp
@@ -949,6 +949,10 @@ void Renderer::BlitScreen(VkRenderPass render_pass, const TargetRectangle& dst_r
     post_processor->BlitFromTexture(left_rect, src_rect, src_tex, 0, render_pass);
     post_processor->BlitFromTexture(right_rect, src_rect, src_tex, 1, render_pass);
   }
+  else if (g_ActiveConfig.iStereoMode == STEREO_QUADBUFFER)
+  {
+    post_processor->BlitFromTexture(dst_rect, src_rect, src_tex, -1, render_pass);
+  }
   else
   {
     post_processor->BlitFromTexture(dst_rect, src_rect, src_tex, 0, render_pass);
@@ -1186,6 +1190,11 @@ void Renderer::CheckForConfigChanges()
     m_swap_chain->SetVSync(g_ActiveConfig.IsVSync());
   }
 
+  // For quad-buffered stereo we need to change the layer count, so recreate the swap chain.
+  if (m_swap_chain &&
+      (g_ActiveConfig.iStereoMode == STEREO_QUADBUFFER) != m_swap_chain->IsStereoEnabled())
+    ResizeSwapChain();
+
   // Wipe sampler cache if force texture filtering or anisotropy changes.
   if (anisotropy_changed || force_texture_filtering_changed)
     ResetSamplerStates();
diff --git a/Source/Core/VideoBackends/Vulkan/SwapChain.cpp b/Source/Core/VideoBackends/Vulkan/SwapChain.cpp
index d43a0e4499..21009510bb 100644
--- a/Source/Core/VideoBackends/Vulkan/SwapChain.cpp
+++ b/Source/Core/VideoBackends/Vulkan/SwapChain.cpp
@@ -320,6 +320,9 @@ bool SwapChain::CreateSwapChain()
     return false;
   }
 
+  // Select the number of image layers for Quad-Buffered stereoscopy
+  uint32_t image_layers = g_ActiveConfig.iStereoMode == STEREO_QUADBUFFER ? 2 : 1;
+
   // Store the old/current swap chain when recreating for resize
   VkSwapchainKHR old_swap_chain = m_swap_chain;
 
@@ -333,7 +336,7 @@ bool SwapChain::CreateSwapChain()
                                               m_surface_format.format,
                                               m_surface_format.colorSpace,
                                               size,
-                                              1,
+                                              image_layers,
                                               image_usage,
                                               VK_SHARING_MODE_EXCLUSIVE,
                                               0,
@@ -359,6 +362,7 @@ bool SwapChain::CreateSwapChain()
 
   m_width = size.width;
   m_height = size.height;
+  m_layers = image_layers;
   return true;
 }
 
@@ -400,7 +404,7 @@ bool SwapChain::SetupSwapChainImages()
                                                 &view,
                                                 m_width,
                                                 m_height,
-                                                1};
+                                                m_layers};
 
     res = vkCreateFramebuffer(g_vulkan_context->GetDevice(), &framebuffer_info, nullptr,
                               &image.framebuffer);
diff --git a/Source/Core/VideoBackends/Vulkan/SwapChain.h b/Source/Core/VideoBackends/Vulkan/SwapChain.h
index 0ff480d64c..37c3460796 100644
--- a/Source/Core/VideoBackends/Vulkan/SwapChain.h
+++ b/Source/Core/VideoBackends/Vulkan/SwapChain.h
@@ -32,6 +32,7 @@ public:
   VkSurfaceKHR GetSurface() const { return m_surface; }
   VkSurfaceFormatKHR GetSurfaceFormat() const { return m_surface_format; }
   bool IsVSyncEnabled() const { return m_vsync_enabled; }
+  bool IsStereoEnabled() const { return m_layers == 2; }
   VkSwapchainKHR GetSwapChain() const { return m_swap_chain; }
   VkRenderPass GetRenderPass() const { return m_render_pass; }
   u32 GetWidth() const { return m_width; }
@@ -94,6 +95,7 @@ private:
 
   u32 m_width = 0;
   u32 m_height = 0;
+  u32 m_layers = 0;
 };
 
 }  // namespace Vulkan
diff --git a/Source/Core/VideoCommon/PixelShaderGen.cpp b/Source/Core/VideoCommon/PixelShaderGen.cpp
index 335c180b30..cec2c5183d 100644
--- a/Source/Core/VideoCommon/PixelShaderGen.cpp
+++ b/Source/Core/VideoCommon/PixelShaderGen.cpp
@@ -606,6 +606,8 @@ ShaderCode GeneratePixelShaderCode(APIType ApiType, const pixel_shader_uid_data*
                 GetInterpolationQualifier(uid_data->msaa, uid_data->ssaa),
                 uid_data->genMode_numtexgens + 2);
     }
+    out.Write(",\n  in float clipDist0 : SV_ClipDistance0\n");
+    out.Write(",\n  in float clipDist1 : SV_ClipDistance1\n");
     if (uid_data->stereo)
       out.Write(",\n  in uint layer : SV_RenderTargetArrayIndex\n");
     out.Write("        ) {\n");
diff --git a/Source/Core/VideoCommon/VideoConfig.h b/Source/Core/VideoCommon/VideoConfig.h
index ef4c33fa43..e706cea1c3 100644
--- a/Source/Core/VideoCommon/VideoConfig.h
+++ b/Source/Core/VideoCommon/VideoConfig.h
@@ -47,6 +47,7 @@ enum StereoMode
   STEREO_SBS,
   STEREO_TAB,
   STEREO_ANAGLYPH,
+  STEREO_QUADBUFFER,
   STEREO_3DVISION
 };