diff --git a/Source/Core/VideoBackends/OGL/Render.cpp b/Source/Core/VideoBackends/OGL/Render.cpp
index a357a8d2dc..546556c440 100644
--- a/Source/Core/VideoBackends/OGL/Render.cpp
+++ b/Source/Core/VideoBackends/OGL/Render.cpp
@@ -652,6 +652,10 @@ Renderer::Renderer(std::unique_ptr<GLContext> main_gl_context, float backbuffer_
 
     // Desktop OpenGL can't have the Android Extension Pack
     g_ogl_config.bSupportsAEP = false;
+
+    // Desktop GL requires GL_PROGRAM_POINT_SIZE set to use gl_PointSize in shaders.
+    // It is implicitly enabled in GLES.
+    glEnable(GL_PROGRAM_POINT_SIZE);
   }
 
   // Either method can do early-z tests. See PixelShaderGen for details.
@@ -1108,8 +1112,6 @@ void Renderer::CheckForSurfaceResize()
 void Renderer::BeginUtilityDrawing()
 {
   ::Renderer::BeginUtilityDrawing();
-
-  glEnable(GL_PROGRAM_POINT_SIZE);
   if (g_ActiveConfig.backend_info.bSupportsDepthClamp)
   {
     glDisable(GL_CLIP_DISTANCE0);
@@ -1120,8 +1122,6 @@ void Renderer::BeginUtilityDrawing()
 void Renderer::EndUtilityDrawing()
 {
   ::Renderer::EndUtilityDrawing();
-
-  glDisable(GL_PROGRAM_POINT_SIZE);
   if (g_ActiveConfig.backend_info.bSupportsDepthClamp)
   {
     glEnable(GL_CLIP_DISTANCE0);