diff --git a/Source/Core/DolphinWX/Frame.cpp b/Source/Core/DolphinWX/Frame.cpp
index d2b396aa3d..05f01a9cb0 100644
--- a/Source/Core/DolphinWX/Frame.cpp
+++ b/Source/Core/DolphinWX/Frame.cpp
@@ -1141,7 +1141,7 @@ void CFrame::OnMouse(wxMouseEvent& event)
 
 void CFrame::OnFocusChange(wxFocusEvent& event)
 {
-	if (SConfig::GetInstance().m_PauseOnFocusLost)
+	if (SConfig::GetInstance().m_PauseOnFocusLost && Core::IsRunningAndStarted())
 	{
 		if (RendererHasFocus())
 		{