diff --git a/Source/Core/Common/Debug/CodeTrace.cpp b/Source/Core/Common/Debug/CodeTrace.cpp
index d1cb913356..2b2694c1dd 100644
--- a/Source/Core/Common/Debug/CodeTrace.cpp
+++ b/Source/Core/Common/Debug/CodeTrace.cpp
@@ -60,7 +60,7 @@ InstructionAttributes CodeTrace::GetInstructionAttributes(const TraceOutput& ins
   // decision has to be made, otherwise used afterwards on a log file.
   InstructionAttributes tmp_attributes;
   tmp_attributes.instruction = instruction.instruction;
-  tmp_attributes.address = PC;
+  tmp_attributes.address = PowerPC::ppcState.pc;
   std::string instr = instruction.instruction;
   std::smatch match;
 
@@ -108,9 +108,9 @@ TraceOutput CodeTrace::SaveCurrentInstruction() const
 {
   // Quickly save instruction and memory target for fast logging.
   TraceOutput output;
-  const std::string instr = PowerPC::debug_interface.Disassemble(PC);
+  const std::string instr = PowerPC::debug_interface.Disassemble(PowerPC::ppcState.pc);
   output.instruction = instr;
-  output.address = PC;
+  output.address = PowerPC::ppcState.pc;
 
   if (IsInstructionLoadStore(output.instruction))
     output.memory_target = PowerPC::debug_interface.GetMemoryAddressFromInstruction(instr);
diff --git a/Source/Core/Core/Boot/Boot.cpp b/Source/Core/Core/Boot/Boot.cpp
index a9bbf759da..9aa2e299e0 100644
--- a/Source/Core/Core/Boot/Boot.cpp
+++ b/Source/Core/Core/Boot/Boot.cpp
@@ -473,7 +473,7 @@ bool CBoot::Load_BS2(Core::System& system, const std::string& boot_rom_filename)
   PowerPC::ppcState.spr[SPR_DBAT3L] = 0xfff00001;
   SetupBAT(/*is_wii*/ false);
 
-  PC = 0x81200150;
+  PowerPC::ppcState.pc = 0x81200150;
   return true;
 }
 
@@ -572,7 +572,7 @@ bool CBoot::BootUp(Core::System& system, std::unique_ptr<BootParameters> boot)
 
       SConfig::OnNewTitleLoad();
 
-      PC = executable.reader->GetEntryPoint();
+      PowerPC::ppcState.pc = executable.reader->GetEntryPoint();
 
       if (executable.reader->LoadSymbols())
       {
diff --git a/Source/Core/Core/Boot/Boot_BS2Emu.cpp b/Source/Core/Core/Boot/Boot_BS2Emu.cpp
index 48dafc9443..7371512e04 100644
--- a/Source/Core/Core/Boot/Boot_BS2Emu.cpp
+++ b/Source/Core/Core/Boot/Boot_BS2Emu.cpp
@@ -57,10 +57,10 @@ void PresetTimeBaseTicks()
 
 void CBoot::RunFunction(u32 address)
 {
-  PC = address;
+  PowerPC::ppcState.pc = address;
   LR = 0x00;
 
-  while (PC != 0x00)
+  while (PowerPC::ppcState.pc != 0x00)
     PowerPC::SingleStep();
 }
 
@@ -206,7 +206,7 @@ bool CBoot::RunApploader(bool is_wii, const DiscIO::VolumeDisc& volume,
   HLE::UnPatch("AppLoaderReport");
 
   // return
-  PC = PowerPC::ppcState.gpr[3];
+  PowerPC::ppcState.pc = PowerPC::ppcState.gpr[3];
 
   return true;
 }
diff --git a/Source/Core/Core/Debugger/Debugger_SymbolMap.cpp b/Source/Core/Core/Debugger/Debugger_SymbolMap.cpp
index fd60a4e58b..2283d368fd 100644
--- a/Source/Core/Core/Debugger/Debugger_SymbolMap.cpp
+++ b/Source/Core/Core/Debugger/Debugger_SymbolMap.cpp
@@ -106,7 +106,7 @@ void PrintCallstack(Common::Log::LogType type, Common::Log::LogLevel level)
     GENERIC_LOG_FMT(type, level, " LR = 0 - this is bad");
   }
 
-  if (g_symbolDB.GetDescription(PC) != g_symbolDB.GetDescription(LR))
+  if (g_symbolDB.GetDescription(PowerPC::ppcState.pc) != g_symbolDB.GetDescription(LR))
   {
     GENERIC_LOG_FMT(type, level, " * {}  [ LR = {:08x} ]", g_symbolDB.GetDescription(LR), LR);
   }
diff --git a/Source/Core/Core/GeckoCode.cpp b/Source/Core/Core/GeckoCode.cpp
index f69eb7f9bf..85585d17c1 100644
--- a/Source/Core/Core/GeckoCode.cpp
+++ b/Source/Core/Core/GeckoCode.cpp
@@ -268,7 +268,7 @@ void RunCodeHandler()
   PowerPC::HostWrite_U32(SP + 8, SP);
   // SP + 4 is reserved for the codehandler to save LR to the stack.
   PowerPC::HostWrite_U32(SFP, SP + 8);  // Real stack frame
-  PowerPC::HostWrite_U32(PC, SP + 12);
+  PowerPC::HostWrite_U32(PowerPC::ppcState.pc, SP + 12);
   PowerPC::HostWrite_U32(LR, SP + 16);
   PowerPC::HostWrite_U32(PowerPC::ppcState.cr.Get(), SP + 20);
   // Registers FPR0->13 are volatile
@@ -280,9 +280,9 @@ void RunCodeHandler()
   DEBUG_LOG_FMT(ACTIONREPLAY,
                 "GeckoCodes: Initiating phantom branch-and-link. "
                 "PC = {:#010x}, SP = {:#010x}, SFP = {:#010x}",
-                PC, SP, SFP);
+                PowerPC::ppcState.pc, SP, SFP);
   LR = HLE_TRAMPOLINE_ADDRESS;
-  PC = NPC = ENTRY_POINT;
+  PowerPC::ppcState.pc = NPC = ENTRY_POINT;
 }
 
 }  // namespace Gecko
diff --git a/Source/Core/Core/HLE/HLE_OS.cpp b/Source/Core/Core/HLE/HLE_OS.cpp
index d5caa5a215..35832dc68b 100644
--- a/Source/Core/Core/HLE/HLE_OS.cpp
+++ b/Source/Core/Core/HLE/HLE_OS.cpp
@@ -37,7 +37,8 @@ void HLE_OSPanic()
   StringPopBackIf(&msg, '\n');
 
   PanicAlertFmt("OSPanic: {}: {}", error, msg);
-  ERROR_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| OSPanic: {}: {}", LR, PC, error, msg);
+  ERROR_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| OSPanic: {}: {}", LR, PowerPC::ppcState.pc, error,
+                msg);
 
   NPC = LR;
 }
@@ -79,7 +80,8 @@ void HLE_GeneralDebugPrint(ParameterType parameter_type)
 
   StringPopBackIf(&report_message, '\n');
 
-  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PC, SHIFTJISToUTF8(report_message));
+  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PowerPC::ppcState.pc,
+                 SHIFTJISToUTF8(report_message));
 }
 
 // Generalized function for printing formatted string using parameter list.
@@ -115,7 +117,8 @@ void HLE_write_console()
 
   StringPopBackIf(&report_message, '\n');
 
-  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PC, SHIFTJISToUTF8(report_message));
+  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PowerPC::ppcState.pc,
+                 SHIFTJISToUTF8(report_message));
 }
 
 // Log (v)dprintf message if fd is 1 (stdout) or 2 (stderr)
@@ -126,7 +129,8 @@ void HLE_LogDPrint(ParameterType parameter_type)
 
   std::string report_message = GetStringVA(4, parameter_type);
   StringPopBackIf(&report_message, '\n');
-  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PC, SHIFTJISToUTF8(report_message));
+  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PowerPC::ppcState.pc,
+                 SHIFTJISToUTF8(report_message));
 }
 
 // Log dprintf message
@@ -164,7 +168,8 @@ void HLE_LogFPrint(ParameterType parameter_type)
 
   std::string report_message = GetStringVA(4, parameter_type);
   StringPopBackIf(&report_message, '\n');
-  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PC, SHIFTJISToUTF8(report_message));
+  NOTICE_LOG_FMT(OSREPORT_HLE, "{:08x}->{:08x}| {}", LR, PowerPC::ppcState.pc,
+                 SHIFTJISToUTF8(report_message));
 }
 
 // Log fprintf message
diff --git a/Source/Core/Core/HW/CPU.cpp b/Source/Core/Core/HW/CPU.cpp
index 05898b1f8c..1188a1022a 100644
--- a/Source/Core/Core/HW/CPU.cpp
+++ b/Source/Core/Core/HW/CPU.cpp
@@ -111,7 +111,8 @@ void Run()
       // If watchpoints are enabled, any instruction could be a breakpoint.
       if (PowerPC::GetMode() != PowerPC::CoreMode::Interpreter)
       {
-        if (PowerPC::breakpoints.IsAddressBreakPoint(PC) || PowerPC::memchecks.HasAny())
+        if (PowerPC::breakpoints.IsAddressBreakPoint(PowerPC::ppcState.pc) ||
+            PowerPC::memchecks.HasAny())
         {
           s_state = State::Stepping;
           PowerPC::CoreMode old_mode = PowerPC::GetMode();
diff --git a/Source/Core/Core/HW/DSP.cpp b/Source/Core/Core/HW/DSP.cpp
index c9578d1f39..c655ffc95a 100644
--- a/Source/Core/Core/HW/DSP.cpp
+++ b/Source/Core/Core/HW/DSP.cpp
@@ -572,7 +572,8 @@ static void Do_ARAM_DMA()
   {
     // ARAM -> MRAM
     DEBUG_LOG_FMT(DSPINTERFACE, "DMA {:08x} bytes from ARAM {:08x} to MRAM {:08x} PC: {:08x}",
-                  state.aram_dma.Cnt.count, state.aram_dma.ARAddr, state.aram_dma.MMAddr, PC);
+                  state.aram_dma.Cnt.count, state.aram_dma.ARAddr, state.aram_dma.MMAddr,
+                  PowerPC::ppcState.pc);
 
     // Outgoing data from ARAM is mirrored every 64MB (verified on real HW)
     state.aram_dma.ARAddr &= 0x3ffffff;
@@ -620,7 +621,8 @@ static void Do_ARAM_DMA()
   {
     // MRAM -> ARAM
     DEBUG_LOG_FMT(DSPINTERFACE, "DMA {:08x} bytes from MRAM {:08x} to ARAM {:08x} PC: {:08x}",
-                  state.aram_dma.Cnt.count, state.aram_dma.MMAddr, state.aram_dma.ARAddr, PC);
+                  state.aram_dma.Cnt.count, state.aram_dma.MMAddr, state.aram_dma.ARAddr,
+                  PowerPC::ppcState.pc);
 
     // Incoming data into ARAM is mirrored every 64MB (verified on real HW)
     state.aram_dma.ARAddr &= 0x3ffffff;
diff --git a/Source/Core/Core/HW/Memmap.cpp b/Source/Core/Core/HW/Memmap.cpp
index a9b616751b..4e458df0d2 100644
--- a/Source/Core/Core/HW/Memmap.cpp
+++ b/Source/Core/Core/HW/Memmap.cpp
@@ -482,7 +482,8 @@ u8* MemoryManager::GetPointer(u32 address) const
       return m_exram + (address & GetExRamMask());
   }
 
-  PanicAlertFmt("Unknown Pointer {:#010x} PC {:#010x} LR {:#010x}", address, PC, LR);
+  PanicAlertFmt("Unknown Pointer {:#010x} PC {:#010x} LR {:#010x}", address, PowerPC::ppcState.pc,
+                LR);
   return nullptr;
 }
 
diff --git a/Source/Core/Core/IOS/IOS.cpp b/Source/Core/Core/IOS/IOS.cpp
index 4e9996c44d..6e0c5a0731 100644
--- a/Source/Core/Core/IOS/IOS.cpp
+++ b/Source/Core/Core/IOS/IOS.cpp
@@ -200,7 +200,7 @@ static void ResetAndPausePPC()
   auto& memory = system.GetMemory();
   memory.Write_U32(0x48000000, 0x00000000);  // b 0x0
   PowerPC::Reset();
-  PC = 0;
+  PowerPC::ppcState.pc = 0;
 }
 
 static void ReleasePPC()
@@ -212,7 +212,7 @@ static void ReleasePPC()
   // NAND titles start with address translation off at 0x3400 (via the PPC bootstub)
   // The state of other CPU registers (like the BAT registers) doesn't matter much
   // because the realmode code at 0x3400 initializes everything itself anyway.
-  PC = 0x3400;
+  PowerPC::ppcState.pc = 0x3400;
 }
 
 static void ReleasePPCAncast()
@@ -223,7 +223,7 @@ static void ReleasePPCAncast()
   // On a real console the Espresso verifies and decrypts the Ancast image,
   // then jumps to the decrypted ancast body.
   // The Ancast loader already did this, so just jump to the decrypted body.
-  PC = ESPRESSO_ANCAST_LOCATION_VIRT + sizeof(EspressoAncastHeader);
+  PowerPC::ppcState.pc = ESPRESSO_ANCAST_LOCATION_VIRT + sizeof(EspressoAncastHeader);
 }
 
 void RAMOverrideForIOSMemoryValues(MemorySetupType setup_type)
diff --git a/Source/Core/Core/IOS/MIOS.cpp b/Source/Core/Core/IOS/MIOS.cpp
index 9a67f0f95a..30d43a4e19 100644
--- a/Source/Core/Core/IOS/MIOS.cpp
+++ b/Source/Core/Core/IOS/MIOS.cpp
@@ -79,7 +79,7 @@ bool Load()
   const PowerPC::CoreMode core_mode = PowerPC::GetMode();
   PowerPC::SetMode(PowerPC::CoreMode::Interpreter);
   MSR.Hex = 0;
-  PC = 0x3400;
+  PowerPC::ppcState.pc = 0x3400;
   NOTICE_LOG_FMT(IOS, "Loaded MIOS and bootstrapped PPC.");
 
   // IOS writes 0 to 0x30f8 before bootstrapping the PPC. Once started, the IPL eventually writes
diff --git a/Source/Core/Core/PatchEngine.cpp b/Source/Core/Core/PatchEngine.cpp
index a525e67261..8d313ec3d3 100644
--- a/Source/Core/Core/PatchEngine.cpp
+++ b/Source/Core/Core/PatchEngine.cpp
@@ -320,7 +320,7 @@ bool ApplyFramePatches()
     DEBUG_LOG_FMT(ACTIONREPLAY,
                   "Need to retry later. CPU configuration is currently incorrect. PC = {:#010x}, "
                   "MSR = {:#010x}",
-                  PC, MSR.Hex);
+                  PowerPC::ppcState.pc, MSR.Hex);
     return false;
   }
 
diff --git a/Source/Core/Core/PowerPC/CachedInterpreter/CachedInterpreter.cpp b/Source/Core/Core/PowerPC/CachedInterpreter/CachedInterpreter.cpp
index a0496b5437..94c271be49 100644
--- a/Source/Core/Core/PowerPC/CachedInterpreter/CachedInterpreter.cpp
+++ b/Source/Core/Core/PowerPC/CachedInterpreter/CachedInterpreter.cpp
@@ -81,7 +81,7 @@ void CachedInterpreter::ExecuteOneBlock()
   const u8* normal_entry = m_block_cache.Dispatch();
   if (!normal_entry)
   {
-    Jit(PC);
+    Jit(PowerPC::ppcState.pc);
     return;
   }
 
@@ -136,7 +136,7 @@ void CachedInterpreter::SingleStep()
 
 static void EndBlock(UGeckoInstruction data)
 {
-  PC = NPC;
+  PowerPC::ppcState.pc = NPC;
   PowerPC::ppcState.downcount -= data.hex;
   PowerPC::UpdatePerformanceMonitor(data.hex, 0, 0);
 }
@@ -153,7 +153,7 @@ static void UpdateNumFloatingPointInstructions(UGeckoInstruction data)
 
 static void WritePC(UGeckoInstruction data)
 {
-  PC = data.hex;
+  PowerPC::ppcState.pc = data.hex;
   NPC = data.hex + 4;
 }
 
@@ -239,7 +239,8 @@ void CachedInterpreter::Jit(u32 address)
     ClearCache();
   }
 
-  const u32 nextPC = analyzer.Analyze(PC, &code_block, &m_code_buffer, m_code_buffer.size());
+  const u32 nextPC =
+      analyzer.Analyze(PowerPC::ppcState.pc, &code_block, &m_code_buffer, m_code_buffer.size());
   if (code_block.m_memory_exception)
   {
     // Address of instruction could not be translated
@@ -250,9 +251,9 @@ void CachedInterpreter::Jit(u32 address)
     return;
   }
 
-  JitBlock* b = m_block_cache.AllocateBlock(PC);
+  JitBlock* b = m_block_cache.AllocateBlock(PowerPC::ppcState.pc);
 
-  js.blockStart = PC;
+  js.blockStart = PowerPC::ppcState.pc;
   js.firstFPInstructionFound = false;
   js.fifoBytesSinceCheck = 0;
   js.downcountAmount = 0;
diff --git a/Source/Core/Core/PowerPC/Expression.cpp b/Source/Core/Core/PowerPC/Expression.cpp
index 87b3a5624a..afc4a74378 100644
--- a/Source/Core/Core/PowerPC/Expression.cpp
+++ b/Source/Core/Core/PowerPC/Expression.cpp
@@ -264,7 +264,7 @@ void Expression::SynchronizeBindings(SynchronizeDirection dir) const
       break;
     case VarBindingType::PCtr:
       if (dir == SynchronizeDirection::From)
-        v->value = static_cast<double>(PC);
+        v->value = static_cast<double>(PowerPC::ppcState.pc);
       break;
     }
   }
diff --git a/Source/Core/Core/PowerPC/GDBStub.cpp b/Source/Core/Core/PowerPC/GDBStub.cpp
index 3e5c90a1d6..98ca6c44eb 100644
--- a/Source/Core/Core/PowerPC/GDBStub.cpp
+++ b/Source/Core/Core/PowerPC/GDBStub.cpp
@@ -429,7 +429,7 @@ static void ReadRegister()
     switch (id)
     {
     case 64:
-      wbe32hex(reply, PC);
+      wbe32hex(reply, PowerPC::ppcState.pc);
       break;
     case 65:
       wbe32hex(reply, MSR.Hex);
@@ -641,7 +641,7 @@ static void WriteRegister()
     switch (id)
     {
     case 64:
-      PC = re32hex(bufptr);
+      PowerPC::ppcState.pc = re32hex(bufptr);
       break;
     case 65:
       MSR.Hex = re32hex(bufptr);
@@ -1122,8 +1122,8 @@ bool JustConnected()
 void SendSignal(Signal signal)
 {
   char bfr[128] = {};
-  fmt::format_to(bfr, "T{:02x}{:02x}:{:08x};{:02x}:{:08x};", static_cast<u8>(signal), 64, PC, 1,
-                 GPR(1));
+  fmt::format_to(bfr, "T{:02x}{:02x}:{:08x};{:02x}:{:08x};", static_cast<u8>(signal), 64,
+                 PowerPC::ppcState.pc, 1, GPR(1));
   SendReply(bfr);
 }
 }  // namespace GDBStub
diff --git a/Source/Core/Core/PowerPC/Interpreter/Interpreter.cpp b/Source/Core/Core/PowerPC/Interpreter/Interpreter.cpp
index 7825d492bf..d4102c0a70 100644
--- a/Source/Core/Core/PowerPC/Interpreter/Interpreter.cpp
+++ b/Source/Core/Core/PowerPC/Interpreter/Interpreter.cpp
@@ -73,8 +73,8 @@ bool IsInvalidPairedSingleExecution(UGeckoInstruction inst)
 
 void UpdatePC()
 {
-  last_pc = PC;
-  PC = NPC;
+  last_pc = PowerPC::ppcState.pc;
+  PowerPC::ppcState.pc = NPC;
 }
 }  // Anonymous namespace
 
@@ -126,12 +126,13 @@ static void Trace(const UGeckoInstruction& inst)
     fregs += fmt::format("f{:02d}: {:08x} {:08x} ", i, ps.PS0AsU64(), ps.PS1AsU64());
   }
 
-  const std::string ppc_inst = Common::GekkoDisassembler::Disassemble(inst.hex, PC);
+  const std::string ppc_inst =
+      Common::GekkoDisassembler::Disassemble(inst.hex, PowerPC::ppcState.pc);
   DEBUG_LOG_FMT(POWERPC,
                 "INTER PC: {:08x} SRR0: {:08x} SRR1: {:08x} CRval: {:016x} "
                 "FPSCR: {:08x} MSR: {:08x} LR: {:08x} {} {:08x} {}",
-                PC, SRR0, SRR1, PowerPC::ppcState.cr.fields[0], FPSCR.Hex, MSR.Hex,
-                PowerPC::ppcState.spr[8], regs, inst.hex, ppc_inst);
+                PowerPC::ppcState.pc, SRR0, SRR1, PowerPC::ppcState.cr.fields[0], FPSCR.Hex,
+                MSR.Hex, PowerPC::ppcState.spr[8], regs, inst.hex, ppc_inst);
 }
 
 bool Interpreter::HandleFunctionHooking(u32 address)
@@ -144,20 +145,25 @@ bool Interpreter::HandleFunctionHooking(u32 address)
 
 int Interpreter::SingleStepInner()
 {
-  if (HandleFunctionHooking(PC))
+  if (HandleFunctionHooking(PowerPC::ppcState.pc))
   {
     UpdatePC();
     return PPCTables::GetOpInfo(m_prev_inst)->numCycles;
   }
 
-  NPC = PC + sizeof(UGeckoInstruction);
-  m_prev_inst.hex = PowerPC::Read_Opcode(PC);
+  NPC = PowerPC::ppcState.pc + sizeof(UGeckoInstruction);
+  m_prev_inst.hex = PowerPC::Read_Opcode(PowerPC::ppcState.pc);
 
   // Uncomment to trace the interpreter
-  // if ((PC & 0x00FFFFFF) >= 0x000AB54C && (PC & 0x00FFFFFF) <= 0x000AB624)
+  // if ((PowerPC::ppcState.pc & 0x00FFFFFF) >= 0x000AB54C &&
+  //     (PowerPC::ppcState.pc & 0x00FFFFFF) <= 0x000AB624)
+  // {
   //   s_start_trace = true;
+  // }
   // else
+  // {
   //   s_start_trace = false;
+  // }
 
   if (s_start_trace)
   {
@@ -228,7 +234,7 @@ void Interpreter::SingleStep()
   if (PowerPC::ppcState.Exceptions != 0)
   {
     PowerPC::CheckExceptions();
-    PC = NPC;
+    PowerPC::ppcState.pc = NPC;
   }
 }
 
@@ -256,7 +262,7 @@ void Interpreter::Run()
     if (Config::Get(Config::MAIN_ENABLE_DEBUGGING))
     {
 #ifdef SHOW_HISTORY
-      s_pc_block_vec.push_back(PC);
+      s_pc_block_vec.push_back(PowerPC::ppcState.pc);
       if (s_pc_block_vec.size() > s_show_blocks)
         s_pc_block_vec.erase(s_pc_block_vec.begin());
 #endif
@@ -270,13 +276,13 @@ void Interpreter::Run()
         while (!m_end_block)
         {
 #ifdef SHOW_HISTORY
-          s_pc_vec.push_back(PC);
+          s_pc_vec.push_back(PowerPC::ppcState.pc);
           if (s_pc_vec.size() > s_show_steps)
             s_pc_vec.erase(s_pc_vec.begin());
 #endif
 
           // 2: check for breakpoint
-          if (PowerPC::breakpoints.IsAddressBreakPoint(PC))
+          if (PowerPC::breakpoints.IsAddressBreakPoint(PowerPC::ppcState.pc))
           {
 #ifdef SHOW_HISTORY
             NOTICE_LOG_FMT(POWERPC, "----------------------------");
@@ -297,12 +303,12 @@ void Interpreter::Run()
               NOTICE_LOG_FMT(POWERPC, "PC: {:#010x}", s_pc_vec[j]);
             }
 #endif
-            INFO_LOG_FMT(POWERPC, "Hit Breakpoint - {:08x}", PC);
+            INFO_LOG_FMT(POWERPC, "Hit Breakpoint - {:08x}", PowerPC::ppcState.pc);
             CPU::Break();
             if (GDBStub::IsActive())
               GDBStub::TakeControl();
-            if (PowerPC::breakpoints.IsTempBreakPoint(PC))
-              PowerPC::breakpoints.Remove(PC);
+            if (PowerPC::breakpoints.IsTempBreakPoint(PowerPC::ppcState.pc))
+              PowerPC::breakpoints.Remove(PowerPC::ppcState.pc);
 
             Host_UpdateDisasmDialog();
             return;
@@ -339,7 +345,7 @@ void Interpreter::unknown_instruction(UGeckoInstruction inst)
   NOTICE_LOG_FMT(
       POWERPC,
       "\nIntCPU: Unknown instruction {:08x} at PC = {:08x}  last_PC = {:08x}  LR = {:08x}\n",
-      inst.hex, PC, last_pc, LR);
+      inst.hex, PowerPC::ppcState.pc, last_pc, LR);
   for (int i = 0; i < 32; i += 4)
   {
     NOTICE_LOG_FMT(POWERPC, "r{}: {:#010x} r{}: {:#010x} r{}: {:#010x} r{}: {:#010x}", i, rGPR[i],
@@ -347,7 +353,7 @@ void Interpreter::unknown_instruction(UGeckoInstruction inst)
   }
   ASSERT_MSG(POWERPC, 0,
              "\nIntCPU: Unknown instruction {:08x} at PC = {:08x}  last_PC = {:08x}  LR = {:08x}\n",
-             inst.hex, PC, last_pc, LR);
+             inst.hex, PowerPC::ppcState.pc, last_pc, LR);
   if (Core::System::GetInstance().IsPauseOnPanicMode())
     CPU::Break();
 }
diff --git a/Source/Core/Core/PowerPC/Interpreter/Interpreter_Branch.cpp b/Source/Core/Core/PowerPC/Interpreter/Interpreter_Branch.cpp
index 6f51ca9013..6161b1e96a 100644
--- a/Source/Core/Core/PowerPC/Interpreter/Interpreter_Branch.cpp
+++ b/Source/Core/Core/PowerPC/Interpreter/Interpreter_Branch.cpp
@@ -13,14 +13,14 @@
 void Interpreter::bx(UGeckoInstruction inst)
 {
   if (inst.LK)
-    LR = PC + 4;
+    LR = PowerPC::ppcState.pc + 4;
 
   const auto address = u32(SignExt26(inst.LI << 2));
 
   if (inst.AA)
     NPC = address;
   else
-    NPC = PC + address;
+    NPC = PowerPC::ppcState.pc + address;
 
   m_end_block = true;
 }
@@ -42,14 +42,14 @@ void Interpreter::bcx(UGeckoInstruction inst)
   if (counter && condition)
   {
     if (inst.LK)
-      LR = PC + 4;
+      LR = PowerPC::ppcState.pc + 4;
 
     const auto address = u32(SignExt16(s16(inst.BD << 2)));
 
     if (inst.AA)
       NPC = address;
     else
-      NPC = PC + address;
+      NPC = PowerPC::ppcState.pc + address;
   }
 
   m_end_block = true;
@@ -67,7 +67,7 @@ void Interpreter::bcctrx(UGeckoInstruction inst)
   {
     NPC = CTR & (~3);
     if (inst.LK_3)
-      LR = PC + 4;
+      LR = PowerPC::ppcState.pc + 4;
   }
 
   m_end_block = true;
@@ -86,7 +86,7 @@ void Interpreter::bclrx(UGeckoInstruction inst)
   {
     NPC = LR & (~3);
     if (inst.LK_3)
-      LR = PC + 4;
+      LR = PowerPC::ppcState.pc + 4;
   }
 
   m_end_block = true;
@@ -95,7 +95,7 @@ void Interpreter::bclrx(UGeckoInstruction inst)
 void Interpreter::HLEFunction(UGeckoInstruction inst)
 {
   m_end_block = true;
-  HLE::Execute(PC, inst.hex);
+  HLE::Execute(PowerPC::ppcState.pc, inst.hex);
 }
 
 void Interpreter::rfi(UGeckoInstruction inst)
diff --git a/Source/Core/Core/PowerPC/Interpreter/Interpreter_SystemRegisters.cpp b/Source/Core/Core/PowerPC/Interpreter/Interpreter_SystemRegisters.cpp
index d7ec9b3d1b..3dd917fdc5 100644
--- a/Source/Core/Core/PowerPC/Interpreter/Interpreter_SystemRegisters.cpp
+++ b/Source/Core/Core/PowerPC/Interpreter/Interpreter_SystemRegisters.cpp
@@ -372,7 +372,8 @@ void Interpreter::mtspr(UGeckoInstruction inst)
 
   case SPR_WPAR:
     ASSERT_MSG(POWERPC, rSPR(SPR_WPAR) == GPFifo::GATHER_PIPE_PHYSICAL_ADDRESS,
-               "Gather pipe changed to unexpected address {:08x} @ PC {:08x}", rSPR(SPR_WPAR), PC);
+               "Gather pipe changed to unexpected address {:08x} @ PC {:08x}", rSPR(SPR_WPAR),
+               PowerPC::ppcState.pc);
     Core::System::GetInstance().GetGPFifo().ResetGatherPipe();
     break;
 
diff --git a/Source/Core/Core/PowerPC/Jit64/Jit.cpp b/Source/Core/Core/PowerPC/Jit64/Jit.cpp
index ac5a0565e8..ca9512bef3 100644
--- a/Source/Core/Core/PowerPC/Jit64/Jit.cpp
+++ b/Source/Core/Core/PowerPC/Jit64/Jit.cpp
@@ -504,16 +504,16 @@ static void ImHere()
     if (!f)
       f.Open("log64.txt", "w");
 
-    f.WriteString(fmt::format("{0:08x}\n", PC));
+    f.WriteString(fmt::format("{0:08x}\n", PowerPC::ppcState.pc));
   }
-  if (been_here.find(PC) != been_here.end())
+  if (been_here.find(PowerPC::ppcState.pc) != been_here.end())
   {
-    been_here.find(PC)->second++;
-    if ((been_here.find(PC)->second) & 1023)
+    been_here.find(PowerPC::ppcState.pc)->second++;
+    if ((been_here.find(PowerPC::ppcState.pc)->second) & 1023)
       return;
   }
-  INFO_LOG_FMT(DYNA_REC, "I'm here - PC = {:08x} , LR = {:08x}", PC, LR);
-  been_here[PC] = 1;
+  INFO_LOG_FMT(DYNA_REC, "I'm here - PC = {:08x} , LR = {:08x}", PowerPC::ppcState.pc, LR);
+  been_here[PowerPC::ppcState.pc] = 1;
 }
 
 bool Jit64::Cleanup()
@@ -758,7 +758,8 @@ void Jit64::Trace()
   DEBUG_LOG_FMT(DYNA_REC,
                 "JIT64 PC: {:08x} SRR0: {:08x} SRR1: {:08x} FPSCR: {:08x} "
                 "MSR: {:08x} LR: {:08x} {} {}",
-                PC, SRR0, SRR1, FPSCR.Hex, MSR.Hex, PowerPC::ppcState.spr[8], regs, fregs);
+                PowerPC::ppcState.pc, SRR0, SRR1, FPSCR.Hex, MSR.Hex, PowerPC::ppcState.spr[8],
+                regs, fregs);
 }
 
 void Jit64::Jit(u32 em_address)
diff --git a/Source/Core/Core/PowerPC/JitArm64/Jit.cpp b/Source/Core/Core/PowerPC/JitArm64/Jit.cpp
index 2fdf65b0b5..d8c89d3d9d 100644
--- a/Source/Core/Core/PowerPC/JitArm64/Jit.cpp
+++ b/Source/Core/Core/PowerPC/JitArm64/Jit.cpp
@@ -705,7 +705,8 @@ void JitArm64::Trace()
   DEBUG_LOG_FMT(DYNA_REC,
                 "JitArm64 PC: {:08x} SRR0: {:08x} SRR1: {:08x} FPSCR: {:08x} "
                 "MSR: {:08x} LR: {:08x} {} {}",
-                PC, SRR0, SRR1, FPSCR.Hex, MSR.Hex, PowerPC::ppcState.spr[8], regs, fregs);
+                PowerPC::ppcState.pc, SRR0, SRR1, FPSCR.Hex, MSR.Hex, PowerPC::ppcState.spr[8],
+                regs, fregs);
 }
 
 void JitArm64::Jit(u32 em_address)
diff --git a/Source/Core/Core/PowerPC/JitCommon/JitCache.cpp b/Source/Core/Core/PowerPC/JitCommon/JitCache.cpp
index ebd01f06af..8ee5f30caf 100644
--- a/Source/Core/Core/PowerPC/JitCommon/JitCache.cpp
+++ b/Source/Core/Core/PowerPC/JitCommon/JitCache.cpp
@@ -168,10 +168,13 @@ JitBlock* JitBaseBlockCache::GetBlockFromStartAddress(u32 addr, u32 msr)
 
 const u8* JitBaseBlockCache::Dispatch()
 {
-  JitBlock* block = fast_block_map[FastLookupIndexForAddress(PC)];
+  JitBlock* block = fast_block_map[FastLookupIndexForAddress(PowerPC::ppcState.pc)];
 
-  if (!block || block->effectiveAddress != PC || block->msrBits != (MSR.Hex & JIT_CACHE_MSR_MASK))
-    block = MoveBlockIntoFastCache(PC, MSR.Hex & JIT_CACHE_MSR_MASK);
+  if (!block || block->effectiveAddress != PowerPC::ppcState.pc ||
+      block->msrBits != (MSR.Hex & JIT_CACHE_MSR_MASK))
+  {
+    block = MoveBlockIntoFastCache(PowerPC::ppcState.pc, MSR.Hex & JIT_CACHE_MSR_MASK);
+  }
 
   if (!block)
     return nullptr;
diff --git a/Source/Core/Core/PowerPC/JitInterface.cpp b/Source/Core/Core/PowerPC/JitInterface.cpp
index c91d46237a..df6a5edae9 100644
--- a/Source/Core/Core/PowerPC/JitInterface.cpp
+++ b/Source/Core/Core/PowerPC/JitInterface.cpp
@@ -264,20 +264,21 @@ void CompileExceptionCheck(ExceptionType type)
     break;
   }
 
-  if (PC != 0 && (exception_addresses->find(PC)) == (exception_addresses->end()))
+  if (PowerPC::ppcState.pc != 0 &&
+      (exception_addresses->find(PowerPC::ppcState.pc)) == (exception_addresses->end()))
   {
     if (type == ExceptionType::FIFOWrite)
     {
       // Check in case the code has been replaced since: do we need to do this?
-      const OpType optype = PPCTables::GetOpInfo(PowerPC::HostRead_U32(PC))->type;
+      const OpType optype = PPCTables::GetOpInfo(PowerPC::HostRead_U32(PowerPC::ppcState.pc))->type;
       if (optype != OpType::Store && optype != OpType::StoreFP && optype != OpType::StorePS)
         return;
     }
-    exception_addresses->insert(PC);
+    exception_addresses->insert(PowerPC::ppcState.pc);
 
     // Invalidate the JIT block so that it gets recompiled with the external exception check
     // included.
-    g_jit->GetBlockCache()->InvalidateICache(PC, 4, true);
+    g_jit->GetBlockCache()->InvalidateICache(PowerPC::ppcState.pc, 4, true);
   }
 }
 
diff --git a/Source/Core/Core/PowerPC/MMU.cpp b/Source/Core/Core/PowerPC/MMU.cpp
index 59b6131fd1..ade569bbda 100644
--- a/Source/Core/Core/PowerPC/MMU.cpp
+++ b/Source/Core/Core/PowerPC/MMU.cpp
@@ -270,7 +270,7 @@ static T ReadFromHardware(Memory::MemoryManager& memory, u32 em_address)
     return bswap(value);
   }
 
-  PanicAlertFmt("Unable to resolve read address {:x} PC {:x}", em_address, PC);
+  PanicAlertFmt("Unable to resolve read address {:x} PC {:x}", em_address, PowerPC::ppcState.pc);
   if (Core::System::GetInstance().IsPauseOnPanicMode())
   {
     CPU::Break();
@@ -459,7 +459,7 @@ static void WriteToHardware(Core::System& system, Memory::MemoryManager& memory,
     return;
   }
 
-  PanicAlertFmt("Unable to resolve write address {:x} PC {:x}", em_address, PC);
+  PanicAlertFmt("Unable to resolve write address {:x} PC {:x}", em_address, PowerPC::ppcState.pc);
   if (Core::System::GetInstance().IsPauseOnPanicMode())
   {
     CPU::Break();
@@ -578,7 +578,7 @@ static void Memcheck(u32 address, u64 var, bool write, size_t size)
 
   mc->num_hits++;
 
-  const bool pause = mc->Action(&debug_interface, var, address, write, size, PC);
+  const bool pause = mc->Action(&debug_interface, var, address, write, size, PowerPC::ppcState.pc);
   if (!pause)
     return;
 
@@ -1365,7 +1365,7 @@ static void GenerateDSIException(u32 effective_address, bool write)
   if (!Core::System::GetInstance().IsMMUMode())
   {
     PanicAlertFmt("Invalid {} {:#010x}, PC = {:#010x}", write ? "write to" : "read from",
-                  effective_address, PC);
+                  effective_address, PowerPC::ppcState.pc);
     if (Core::System::GetInstance().IsPauseOnPanicMode())
     {
       CPU::Break();
@@ -1393,7 +1393,7 @@ static void GenerateISIException(u32 effective_address)
   NPC = effective_address;
 
   PowerPC::ppcState.Exceptions |= EXCEPTION_ISI;
-  WARN_LOG_FMT(POWERPC, "ISI exception at {:#010x}", PC);
+  WARN_LOG_FMT(POWERPC, "ISI exception at {:#010x}", PowerPC::ppcState.pc);
 }
 
 void SDRUpdated()
diff --git a/Source/Core/Core/PowerPC/PPCTables.cpp b/Source/Core/Core/PowerPC/PPCTables.cpp
index f91ab510d5..aed620a475 100644
--- a/Source/Core/Core/PowerPC/PPCTables.cpp
+++ b/Source/Core/Core/PowerPC/PPCTables.cpp
@@ -51,7 +51,8 @@ GekkoOPInfo* GetOpInfo(UGeckoInstruction inst)
     case 63:
       return m_infoTable63[inst.SUBOP10];
     default:
-      ASSERT_MSG(POWERPC, 0, "GetOpInfo - invalid subtable op {:08x} @ {:08x}", inst.hex, PC);
+      ASSERT_MSG(POWERPC, 0, "GetOpInfo - invalid subtable op {:08x} @ {:08x}", inst.hex,
+                 PowerPC::ppcState.pc);
       return nullptr;
     }
   }
@@ -59,7 +60,8 @@ GekkoOPInfo* GetOpInfo(UGeckoInstruction inst)
   {
     if (info->type == OpType::Invalid)
     {
-      ASSERT_MSG(POWERPC, 0, "GetOpInfo - invalid op {:08x} @ {:08x}", inst.hex, PC);
+      ASSERT_MSG(POWERPC, 0, "GetOpInfo - invalid op {:08x} @ {:08x}", inst.hex,
+                 PowerPC::ppcState.pc);
       return nullptr;
     }
     return m_infoTable[inst.OPCD];
@@ -85,7 +87,7 @@ Interpreter::Instruction GetInterpreterOp(UGeckoInstruction inst)
       return Interpreter::m_op_table63[inst.SUBOP10];
     default:
       ASSERT_MSG(POWERPC, 0, "GetInterpreterOp - invalid subtable op {:08x} @ {:08x}", inst.hex,
-                 PC);
+                 PowerPC::ppcState.pc);
       return nullptr;
     }
   }
@@ -93,7 +95,8 @@ Interpreter::Instruction GetInterpreterOp(UGeckoInstruction inst)
   {
     if (info->type == OpType::Invalid)
     {
-      ASSERT_MSG(POWERPC, 0, "GetInterpreterOp - invalid op {:08x} @ {:08x}", inst.hex, PC);
+      ASSERT_MSG(POWERPC, 0, "GetInterpreterOp - invalid op {:08x} @ {:08x}", inst.hex,
+                 PowerPC::ppcState.pc);
       return nullptr;
     }
     return Interpreter::m_op_table[inst.OPCD];
diff --git a/Source/Core/Core/PowerPC/PowerPC.cpp b/Source/Core/Core/PowerPC/PowerPC.cpp
index 5bba56ad49..592df29859 100644
--- a/Source/Core/Core/PowerPC/PowerPC.cpp
+++ b/Source/Core/Core/PowerPC/PowerPC.cpp
@@ -494,19 +494,19 @@ void CheckExceptions()
     SRR1 = (MSR.Hex & 0x87C0FFFF) | (1 << 30);
     MSR.LE = MSR.ILE;
     MSR.Hex &= ~0x04EF36;
-    PC = NPC = 0x00000400;
+    PowerPC::ppcState.pc = NPC = 0x00000400;
 
     DEBUG_LOG_FMT(POWERPC, "EXCEPTION_ISI");
     ppcState.Exceptions &= ~EXCEPTION_ISI;
   }
   else if (exceptions & EXCEPTION_PROGRAM)
   {
-    SRR0 = PC;
+    SRR0 = PowerPC::ppcState.pc;
     // SRR1 was partially set by GenerateProgramException, so bitwise or is used here
     SRR1 |= MSR.Hex & 0x87C0FFFF;
     MSR.LE = MSR.ILE;
     MSR.Hex &= ~0x04EF36;
-    PC = NPC = 0x00000700;
+    PowerPC::ppcState.pc = NPC = 0x00000700;
 
     DEBUG_LOG_FMT(POWERPC, "EXCEPTION_PROGRAM");
     ppcState.Exceptions &= ~EXCEPTION_PROGRAM;
@@ -517,19 +517,19 @@ void CheckExceptions()
     SRR1 = MSR.Hex & 0x87C0FFFF;
     MSR.LE = MSR.ILE;
     MSR.Hex &= ~0x04EF36;
-    PC = NPC = 0x00000C00;
+    PowerPC::ppcState.pc = NPC = 0x00000C00;
 
-    DEBUG_LOG_FMT(POWERPC, "EXCEPTION_SYSCALL (PC={:08x})", PC);
+    DEBUG_LOG_FMT(POWERPC, "EXCEPTION_SYSCALL (PC={:08x})", PowerPC::ppcState.pc);
     ppcState.Exceptions &= ~EXCEPTION_SYSCALL;
   }
   else if (exceptions & EXCEPTION_FPU_UNAVAILABLE)
   {
     // This happens a lot - GameCube OS uses deferred FPU context switching
-    SRR0 = PC;  // re-execute the instruction
+    SRR0 = PowerPC::ppcState.pc;  // re-execute the instruction
     SRR1 = MSR.Hex & 0x87C0FFFF;
     MSR.LE = MSR.ILE;
     MSR.Hex &= ~0x04EF36;
-    PC = NPC = 0x00000800;
+    PowerPC::ppcState.pc = NPC = 0x00000800;
 
     DEBUG_LOG_FMT(POWERPC, "EXCEPTION_FPU_UNAVAILABLE");
     ppcState.Exceptions &= ~EXCEPTION_FPU_UNAVAILABLE;
@@ -540,11 +540,11 @@ void CheckExceptions()
   }
   else if (exceptions & EXCEPTION_DSI)
   {
-    SRR0 = PC;
+    SRR0 = PowerPC::ppcState.pc;
     SRR1 = MSR.Hex & 0x87C0FFFF;
     MSR.LE = MSR.ILE;
     MSR.Hex &= ~0x04EF36;
-    PC = NPC = 0x00000300;
+    PowerPC::ppcState.pc = NPC = 0x00000300;
     // DSISR and DAR regs are changed in GenerateDSIException()
 
     DEBUG_LOG_FMT(POWERPC, "EXCEPTION_DSI");
@@ -552,11 +552,11 @@ void CheckExceptions()
   }
   else if (exceptions & EXCEPTION_ALIGNMENT)
   {
-    SRR0 = PC;
+    SRR0 = PowerPC::ppcState.pc;
     SRR1 = MSR.Hex & 0x87C0FFFF;
     MSR.LE = MSR.ILE;
     MSR.Hex &= ~0x04EF36;
-    PC = NPC = 0x00000600;
+    PowerPC::ppcState.pc = NPC = 0x00000600;
 
     // TODO crazy amount of DSISR options to check out
 
@@ -586,7 +586,7 @@ void CheckExternalExceptions()
       SRR1 = MSR.Hex & 0x87C0FFFF;
       MSR.LE = MSR.ILE;
       MSR.Hex &= ~0x04EF36;
-      PC = NPC = 0x00000500;
+      PowerPC::ppcState.pc = NPC = 0x00000500;
 
       DEBUG_LOG_FMT(POWERPC, "EXCEPTION_EXTERNAL_INT");
       ppcState.Exceptions &= ~EXCEPTION_EXTERNAL_INT;
@@ -599,7 +599,7 @@ void CheckExternalExceptions()
       SRR1 = MSR.Hex & 0x87C0FFFF;
       MSR.LE = MSR.ILE;
       MSR.Hex &= ~0x04EF36;
-      PC = NPC = 0x00000F00;
+      PowerPC::ppcState.pc = NPC = 0x00000F00;
 
       DEBUG_LOG_FMT(POWERPC, "EXCEPTION_PERFORMANCE_MONITOR");
       ppcState.Exceptions &= ~EXCEPTION_PERFORMANCE_MONITOR;
@@ -610,7 +610,7 @@ void CheckExternalExceptions()
       SRR1 = MSR.Hex & 0x87C0FFFF;
       MSR.LE = MSR.ILE;
       MSR.Hex &= ~0x04EF36;
-      PC = NPC = 0x00000900;
+      PowerPC::ppcState.pc = NPC = 0x00000900;
 
       DEBUG_LOG_FMT(POWERPC, "EXCEPTION_DECREMENTER");
       ppcState.Exceptions &= ~EXCEPTION_DECREMENTER;
@@ -626,7 +626,7 @@ void CheckExternalExceptions()
 
 void CheckBreakPoints()
 {
-  const TBreakPoint* bp = PowerPC::breakpoints.GetBreakpoint(PC);
+  const TBreakPoint* bp = PowerPC::breakpoints.GetBreakpoint(PowerPC::ppcState.pc);
 
   if (!bp || !bp->is_enabled || !EvaluateCondition(bp->condition))
     return;
@@ -642,11 +642,11 @@ void CheckBreakPoints()
     NOTICE_LOG_FMT(MEMMAP,
                    "BP {:08x} {}({:08x} {:08x} {:08x} {:08x} {:08x} {:08x} {:08x} {:08x} {:08x} "
                    "{:08x}) LR={:08x}",
-                   PC, g_symbolDB.GetDescription(PC), GPR(3), GPR(4), GPR(5), GPR(6), GPR(7),
-                   GPR(8), GPR(9), GPR(10), GPR(11), GPR(12), LR);
+                   PowerPC::ppcState.pc, g_symbolDB.GetDescription(PowerPC::ppcState.pc), GPR(3),
+                   GPR(4), GPR(5), GPR(6), GPR(7), GPR(8), GPR(9), GPR(10), GPR(11), GPR(12), LR);
   }
-  if (PowerPC::breakpoints.IsTempBreakPoint(PC))
-    PowerPC::breakpoints.Remove(PC);
+  if (PowerPC::breakpoints.IsTempBreakPoint(PowerPC::ppcState.pc))
+    PowerPC::breakpoints.Remove(PowerPC::ppcState.pc);
 }
 
 void PowerPCState::SetSR(u32 index, u32 value)
diff --git a/Source/Core/Core/PowerPC/PowerPC.h b/Source/Core/Core/PowerPC/PowerPC.h
index 072fcd0abc..7515fbd898 100644
--- a/Source/Core/Core/PowerPC/PowerPC.h
+++ b/Source/Core/Core/PowerPC/PowerPC.h
@@ -245,7 +245,6 @@ void UpdatePerformanceMonitor(u32 cycles, u32 num_load_stores, u32 num_fp_inst);
 #define THRM1(ppc_state) ((UReg_THRM12&)(ppc_state).spr[SPR_THRM1])
 #define THRM2(ppc_state) ((UReg_THRM12&)(ppc_state).spr[SPR_THRM2])
 #define THRM3(ppc_state) ((UReg_THRM3&)(ppc_state).spr[SPR_THRM3])
-#define PC PowerPC::ppcState.pc
 #define NPC PowerPC::ppcState.npc
 #define FPSCR PowerPC::ppcState.fpscr
 #define MSR PowerPC::ppcState.msr
diff --git a/Source/Core/DolphinQt/Debugger/CodeViewWidget.cpp b/Source/Core/DolphinQt/Debugger/CodeViewWidget.cpp
index 77d73a8eff..b4cfcb19eb 100644
--- a/Source/Core/DolphinQt/Debugger/CodeViewWidget.cpp
+++ b/Source/Core/DolphinQt/Debugger/CodeViewWidget.cpp
@@ -167,11 +167,11 @@ CodeViewWidget::CodeViewWidget()
           &CodeViewWidget::FontBasedSizing);
 
   connect(&Settings::Instance(), &Settings::EmulationStateChanged, this, [this] {
-    m_address = PC;
+    m_address = PowerPC::ppcState.pc;
     Update();
   });
   connect(Host::GetInstance(), &Host::UpdateDisasmDialog, this, [this] {
-    m_address = PC;
+    m_address = PowerPC::ppcState.pc;
     Update();
   });
 
@@ -567,9 +567,9 @@ void CodeViewWidget::OnContextMenu()
       menu->addAction(tr("Restore instruction"), this, &CodeViewWidget::OnRestoreInstruction);
 
   QString target;
-  if (addr == PC && running && Core::GetState() == Core::State::Paused)
+  if (addr == PowerPC::ppcState.pc && running && Core::GetState() == Core::State::Paused)
   {
-    const std::string line = PowerPC::debug_interface.Disassemble(PC);
+    const std::string line = PowerPC::debug_interface.Disassemble(PowerPC::ppcState.pc);
     const auto target_it = std::find(line.begin(), line.end(), '\t');
     const auto target_end = std::find(target_it, line.end(), ',');
 
diff --git a/Source/Core/DolphinQt/Debugger/CodeWidget.cpp b/Source/Core/DolphinQt/Debugger/CodeWidget.cpp
index 60f74e52ad..64465dda00 100644
--- a/Source/Core/DolphinQt/Debugger/CodeWidget.cpp
+++ b/Source/Core/DolphinQt/Debugger/CodeWidget.cpp
@@ -451,11 +451,11 @@ void CodeWidget::StepOver()
   if (!CPU::IsStepping())
     return;
 
-  UGeckoInstruction inst = PowerPC::HostRead_Instruction(PC);
+  UGeckoInstruction inst = PowerPC::HostRead_Instruction(PowerPC::ppcState.pc);
   if (inst.LK)
   {
     PowerPC::breakpoints.ClearAllTemporary();
-    PowerPC::breakpoints.Add(PC + 4, true);
+    PowerPC::breakpoints.Add(PowerPC::ppcState.pc + 4, true);
     CPU::EnableStepping(false);
     Core::DisplayMessage(tr("Step over in progress...").toStdString(), 2000);
   }
@@ -495,7 +495,7 @@ void CodeWidget::StepOut()
   // Loop until either the current instruction is a return instruction with no Link flag
   // or a breakpoint is detected so it can step at the breakpoint. If the PC is currently
   // on a breakpoint, skip it.
-  UGeckoInstruction inst = PowerPC::HostRead_Instruction(PC);
+  UGeckoInstruction inst = PowerPC::HostRead_Instruction(PowerPC::ppcState.pc);
   do
   {
     if (WillInstructionReturn(inst))
@@ -507,27 +507,28 @@ void CodeWidget::StepOut()
     if (inst.LK)
     {
       // Step over branches
-      u32 next_pc = PC + 4;
+      u32 next_pc = PowerPC::ppcState.pc + 4;
       do
       {
         PowerPC::SingleStep();
-      } while (PC != next_pc && clock::now() < timeout &&
-               !PowerPC::breakpoints.IsAddressBreakPoint(PC));
+      } while (PowerPC::ppcState.pc != next_pc && clock::now() < timeout &&
+               !PowerPC::breakpoints.IsAddressBreakPoint(PowerPC::ppcState.pc));
     }
     else
     {
       PowerPC::SingleStep();
     }
 
-    inst = PowerPC::HostRead_Instruction(PC);
-  } while (clock::now() < timeout && !PowerPC::breakpoints.IsAddressBreakPoint(PC));
+    inst = PowerPC::HostRead_Instruction(PowerPC::ppcState.pc);
+  } while (clock::now() < timeout &&
+           !PowerPC::breakpoints.IsAddressBreakPoint(PowerPC::ppcState.pc));
 
   PowerPC::SetMode(old_mode);
   CPU::PauseAndLock(false, false);
 
   emit Host::GetInstance()->UpdateDisasmDialog();
 
-  if (PowerPC::breakpoints.IsAddressBreakPoint(PC))
+  if (PowerPC::breakpoints.IsAddressBreakPoint(PowerPC::ppcState.pc))
     Core::DisplayMessage(tr("Breakpoint encountered! Step out aborted.").toStdString(), 2000);
   else if (clock::now() >= timeout)
     Core::DisplayMessage(tr("Step out timed out!").toStdString(), 2000);
@@ -537,19 +538,19 @@ void CodeWidget::StepOut()
 
 void CodeWidget::Skip()
 {
-  PC += 4;
+  PowerPC::ppcState.pc += 4;
   ShowPC();
 }
 
 void CodeWidget::ShowPC()
 {
-  m_code_view->SetAddress(PC, CodeViewWidget::SetAddressUpdate::WithUpdate);
+  m_code_view->SetAddress(PowerPC::ppcState.pc, CodeViewWidget::SetAddressUpdate::WithUpdate);
   Update();
 }
 
 void CodeWidget::SetPC()
 {
-  PC = m_code_view->GetAddress();
+  PowerPC::ppcState.pc = m_code_view->GetAddress();
   Update();
 }
 
diff --git a/Source/Core/UICommon/Disassembler.cpp b/Source/Core/UICommon/Disassembler.cpp
index 590611b12a..62e4d32c6d 100644
--- a/Source/Core/UICommon/Disassembler.cpp
+++ b/Source/Core/UICommon/Disassembler.cpp
@@ -6,9 +6,6 @@
 #include <sstream>
 
 #if defined(HAVE_LLVM)
-// PowerPC.h defines PC.
-// This conflicts with a function that has an argument named PC
-#undef PC
 #include <fmt/format.h>
 #include <llvm-c/Disassembler.h>
 #include <llvm-c/Target.h>
diff --git a/Source/Core/VideoCommon/CommandProcessor.cpp b/Source/Core/VideoCommon/CommandProcessor.cpp
index 1d38b27e86..2e329ba285 100644
--- a/Source/Core/VideoCommon/CommandProcessor.cpp
+++ b/Source/Core/VideoCommon/CommandProcessor.cpp
@@ -684,7 +684,8 @@ void CommandProcessorManager::HandleUnknownOpcode(u8 cmd_byte, const u8* buffer,
       fifo.bFF_Breakpoint.load(std::memory_order_relaxed) ? "true" : "false",
       fifo.bFF_GPLinkEnable.load(std::memory_order_relaxed) ? "true" : "false",
       fifo.bFF_HiWatermarkInt.load(std::memory_order_relaxed) ? "true" : "false",
-      fifo.bFF_LoWatermarkInt.load(std::memory_order_relaxed) ? "true" : "false", PC, LR);
+      fifo.bFF_LoWatermarkInt.load(std::memory_order_relaxed) ? "true" : "false",
+      PowerPC::ppcState.pc, LR);
 
   if (!m_is_fifo_error_seen && !suppress_panic_alert)
   {