diff --git a/Source/Core/DolphinQt/Main.cpp b/Source/Core/DolphinQt/Main.cpp
index 8e1e63d030..7690f16315 100644
--- a/Source/Core/DolphinQt/Main.cpp
+++ b/Source/Core/DolphinQt/Main.cpp
@@ -147,6 +147,15 @@ int main(int argc, char* argv[])
 #endif
 #endif
 
+  // setHighDpiScaleFactorRoundingPolicy was added in 5.14, but default behavior changed in 6.0
+#if (QT_VERSION >= QT_VERSION_CHECK(6, 0, 0))
+  // Set to the previous default behavior
+  QGuiApplication::setHighDpiScaleFactorRoundingPolicy(Qt::HighDpiScaleFactorRoundingPolicy::Round);
+#else
+  QCoreApplication::setAttribute(Qt::AA_EnableHighDpiScaling);
+  QCoreApplication::setAttribute(Qt::AA_UseHighDpiPixmaps);
+#endif
+
   QCoreApplication::setOrganizationName(QStringLiteral("Dolphin Emulator"));
   QCoreApplication::setOrganizationDomain(QStringLiteral("dolphin-emu.org"));
   QCoreApplication::setApplicationName(QStringLiteral("dolphin-emu"));