Launch Multi-Mod Manager
Start the Homebrew Channel (HBC) and load Multi-Mod Manager (MMM). Once you've loaded MMM, move onto the next step.
If you are missing the HBC or it is failing to load any apps (just blackscreens), you will need to launch MMM using another method.
Note: if this Wii was previously modified, and it still has a Forwarder Channel installed, you can use that to launch MMM instead of an exploit. Just save the boot.dol from the app you want to load (ie. SD:\apps\MMM\boot.dol) to the location used by your specific Forwarder Channel (ie. SD:\apps\usbloader\boot.dol). Then start the channel and the app will load.